Science
Grounded in a published scientific framework
General Cognitive operationalizes a peer-reviewed thesis: that multimodal digital biomarkers, integrated over time, form a patient-specific Digital Neuro Fingerprint for precision neurology.
The scientific cornerstone
Merging multimodal digital biomarkers into “Digital Neuro Fingerprints” for precision neurology in dementias: the promise of the right treatment for the right patient at the right time in the age of AI
- Authors
- Ioannis Tarnanas, Azizi Seixas, Martin Wyss, Panagiotis Vlamos, Arzu Çöltekin
- Journal
- Frontiers in Digital Health
- Published
- January 12, 2026
- Type
- Perspective
The paper defines the scientific thesis. General Cognitive is building the infrastructure required to operationalize it.
How the fingerprint is built
Anchor. Enrich. Integrate. Translate.
Validated clinical anchors retain their role. The Digital Neuro Fingerprint is an anchor-linked longitudinal representation — not a standalone diagnosis, a replacement endpoint, or a magical composite score.
- 01
Anchor
Establish a validated clinical reference point that grounds every subsequent measurement.
- 02
Enrich
Layer in multimodal digital signals collected repeatedly in trials and in real-world care.
- 03
Integrate
Combine signals over time into a single, patient-specific longitudinal trajectory.
- 04
Translate
Turn the trajectory into decision-ready measurement for clinicians and study teams.
Academic translation
A research relationship built for validation
General Cognitive has executed a memorandum of understanding with the University of Miami to support a research relationship involving clinical infrastructure, faculty collaboration, and pathways toward peer-reviewed validation.
The relationship is growing through The Media and Innovation Lab, founded and directed by Dr. Azizi Seixas, with areas of collaboration centered on multimodal data, health informatics, study design, clinical translation, and responsible deployment.
All research, patient access, data use, and study activity remain subject to project-specific agreements, institutional approvals, privacy requirements, and IRB review.