Clinical Trials & Digital Biomarkers

Treatment-response analytics and digital cognitive endpoints for modern therapeutics development

Why Digital Cognition Matters in Modern Trials

Traditional clinical trials rely on infrequent, subjective assessments that miss subtle but meaningful treatment effects. Patients visit clinics every few weeks for brief evaluations, creating large gaps in understanding how therapies actually affect day-to-day cognitive function.

Digital biomarkers from continuous multimodal monitoring provide objective, high-resolution data on cognitive changes. This enables earlier go/no-go decisions, better responder identification, and more sensitive endpoints that can reduce trial sizes and durations.

For companies developing treatments across neurology, psychiatry, rare diseases, and aging-related conditions, General Cognitive's platform offers a standardized infrastructure for cognitive measurement that scales across therapeutic areas.

Platform Capabilities

Automated Multimodal Endpoints

Continuous digital measurement replacing subjective clinical scales with objective behavioral data

Responder Stratification

Identify treatment responders early using fine-grained cognitive and behavioral signatures

Cross-Condition Analysis

Unified measurement framework enables comparisons across therapeutic areas and populations

Cognitive-Effects Dashboards

Real-time monitoring of treatment effects on attention, memory, executive function, and mood

Regulatory-Aligned Digital Measures

Endpoints designed for FDA and EMA acceptance with validation documentation

Therapeutic Use Cases

Our platform supports cognitive measurement across diverse conditions and populations

Neurology

Multiple sclerosis, Parkinson's disease, epilepsy, stroke rehabilitation

Psychiatry

Depression, anxiety, bipolar disorder, schizophrenia

Autism & Development

Autism spectrum disorder, ADHD, developmental delays

Alzheimer's & Dementia

Mild cognitive impairment, Alzheimer's disease, frontotemporal dementia

Metabolic & Systemic

Diabetes-related cognitive decline, chronic kidney disease, liver disease

Rare Diseases

Genetic disorders with cognitive manifestations, pediatric metabolic conditions

Benefits for Therapeutics Developers

Reduced Trial Duration

Earlier detection of treatment effects with continuous monitoring vs. periodic assessments

Smaller Sample Sizes

More sensitive endpoints require fewer participants to detect meaningful differences

Better Stratification

Identify responders and optimize patient selection for Phase 2/3 trials

Partner With General Cognitive for Trials

Join leading therapeutics companies using our platform for next-generation cognitive endpoints

Schedule a Consultation